Friday, March 23, 2012

A culinary union flourishes in South Korea

A cold soup serves as a cultural tie between North and South Korea.

Baengnyeong Island, S. Korea

? A local, slice-of-life story from a Monitor correspondent.

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As the mists lift, a hint of the forbidden comes into view just 10 miles across the rough coastal seas. This is one of South Korea?s frontline outposts, located in the Yellow Sea near the Northern Limit Line, the very edge that divides blood brother and political foe North Korea.

But it was not always this way ? before the partition of North and South, the island group was one of four that belonged to the mainland province visible through the mists to the north, now part of an enemy state.

Though cut off from their brethren for six decades, some older island residents still recall a time when they could cross freely. On a cultural level, they carry on a culinary legacy by hosting some of the most authentic versions of a cold noodle dish that also belongs squarely to the North: mul naengmyeon.

On Baengnyeong, in simple restaurants, this icy concoction of buckwheat noodles, beef broth, thinly sliced radishes, and half a boiled egg, is served to a steady stream of island residents, tourists, and South Korean soldiers.

While many visitors are eager to catch a glimpse of the forbidden through binoculars, vestiges of lasting ties lurk beneath the surface of life here. Until relatively recently, visitors from North Korea were said to regularly drift across the precarious waters.

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Source: http://rss.csmonitor.com/~r/csmonitor/globalnews/~3/U9JCF3zoj-g/A-culinary-union-flourishes-in-South-Korea

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Marijuana-like chemicals inhibit human immunodeficiency virus in late-stage AIDS

Wednesday, March 21, 2012

Mount Sinai School of Medicine researchers have discovered that marijuana-like chemicals trigger receptors on human immune cells that can directly inhibit a type of human immunodeficiency virus (HIV) found in late-stage AIDS, according to new findings published online in the journal PLoS ONE.

Medical marijuana is prescribed to treat pain, debilitating weight loss and appetite suppression, side effects that are common in advanced AIDS. This is the first study to reveal how the marijuana receptors found on immune cells?called cannabinoid receptors CB1 and CB2?can influence the spread of the virus. Understanding the effect of these receptors on the virus could help scientists develop new drugs to slow the progression of AIDS.

"We knew that cannabinoid drugs like marijuana can have a therapeutic effect in AIDS patients, but did not understand how they influence the spread of the virus itself," said study author Cristina Costantino, PhD, Postdoctoral Fellow in the Department of Pharmacology and Systems Therapeutics at Mount Sinai School of Medicine. "We wanted to explore cannabinoid receptors as a target for pharmaceutical interventions that treat the symptoms of late-stage AIDS and prevent further progression of the disease without the undesirable side effects of medical marijuana."

HIV infects active immune cells that carry the viral receptor CD4, which makes these cells unable to fight off the infection. In order to spread, the virus requires that "resting" immune cells be activated. In advanced AIDS, HIV mutates so it can infect these resting cells, gaining entry into the cell by using a signaling receptor called CXCR4. By treating the cells with a cannabinoid agonist that triggers CB2, Dr. Costantino and the Mount Sinai team found that CB2 blocked the signaling process, and suppressed infection in resting immune cells.

Triggering CB1 causes the drug high associated with marijuana, making it undesirable for physicians to prescribe. The researchers wanted to explore therapies that would target CB2 only. The Mount Sinai team infected healthy immune cells with HIV, then treated them with a chemical that triggers CB2 called an agonist. They found that the drug reduced the infection of the remaining cells.

"Developing a drug that triggers only CB2 as an adjunctive treatment to standard antiviral medication may help alleviate the symptoms of late-stage AIDS and prevent the virus from spreading," said Dr. Costantino. Because HIV does not use CXCR4 to enhance immune cell infection in the early stages of infection, CB2 agonists appear to be an effective antiviral drug only in late-stage disease.

As a result of this discovery, the research team led by Benjamin Chen, MD, PhD, Associate Professor of Infectious Diseases, and Lakshmi Devi, PhD, Professor of Pharmacology and Systems Therapeutics at Mount Sinai School of Medicine, plans to develop a mouse model of late-stage AIDS in order to test the efficacy of a drug that triggers CB2 in vivo. In 2009 Dr. Chen was part of a team that captured on video for the first time the transfer of HIV from infected T-cells to uninfected T-cells.

###

The Mount Sinai Hospital / Mount Sinai School of Medicine: http://www.mountsinai.org

Thanks to The Mount Sinai Hospital / Mount Sinai School of Medicine for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/118592/Marijuana_like_chemicals_inhibit_human_immunodeficiency_virus_in_late_stage_AIDS

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Thursday, March 22, 2012

OMGPOP?s Sale to Zynga Is One Of Y Combinator?s Biggest Exits To Date

Draw Something ScreenshotsLittle known fact: OMGPOP was actually an early company backed by Paul Graham's incubator Y Combinator. Originally named Iminlikewithyou, it was co-founded by Charles Forman and was part of YC's mid-2006 class. It then toiled for many years building games on its own teen-focused destination site and then on Facebook before taking its Pictionary-like game Draw Something to iOS and Android a little over a month ago. On mobile, the game took off like wildfire, accumulating 35 million downloads and 1 billion drawings in a matter of weeks. Zynga just scooped the company up today for what we're hearing is $180 million plus a $30 million earnout.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/JxLjoZ_dv5U/

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Redistricting wrangle hits Romney and Texas Republicans

AUSTIN, Texas (Reuters) - Texas should be playing a role in Republican politics this year as big as, well, Texas.

The fast-growing state - the most populous by far in the Republican column - has four new seats in the U.S. House of Representatives, a big U.S. Senate race and more than a 10th of the delegates who will choose the party's presidential nominee.

But a racially tinged dispute over redrawing its congressional districts has delayed the Texas primary by almost three months, complicated the U.S. Senate and House contests and altered the race for the White House.

A San Antonio court pushed Texas' primary back to May 29 from March 6 after complaints that a new electoral map drawn by Republicans violated the federal Voting Rights Act by diluting the voting power of blacks and Latinos.

Three of Texas' four new U.S. House seats were created in areas dominated by whites, even though Hispanics and blacks accounted for 90 percent of Texas' population growth since 2000.

The battle sets white Republicans, who have firmly established political control in Texas within the past decade, against rising and strongly Democratic Hispanic and black populations, whose leaders argue that they are being unfairly denied an equal voice in state politics.

The stakes are high both for 2012, when the White House and control of the U.S. Congress are up for grabs, and longer term, when a rapidly growing Hispanic population is expected eventually to disadvantage Republicans and benefit Democrats.

"Republicans can work that racial solidarity thing for a while, but in the end, they've got to do better than 35 percent of the Hispanic vote or their election prospects are not great," said Cal Jillson, a political science professor at Southern Methodist University in Dallas.

States with a history of minority voting rights violations must obtain pre-clearance from either the U.S. Department of Justice or the federal court in Washington, D.C., before they can use new maps. The new voter map in Florida, another fast-growing southern state, has also been subject to legal wrangling this year.

ALREADY A MINORITY

Non-Hispanic whites already account for a minority of Texas' residents, with 45 percent of the population. The state is 38 percent Latino and 12 percent black, numbers expected to continue to rise.

President Barack Obama lost Texas by 11-percentage points in 2008. He got only 26 percent of the white vote, but was backed by 63 percent of Hispanics and 98 percent of blacks, fueling talk that it will not be long before Republican red Texas turns purple, if not Democratic blue.

"We sort of feel like we have the wind at our backs," said Anthony Gutierrez, deputy executive director of the Texas Democratic Party.

Democrats have won Texas in only three of the last 15 presidential elections. The party has not won a statewide election since 1994, and Republicans cemented their control of the state with huge victories in the 2010 midterms.

But even Republicans acknowledge that changing demographics mean the party must appeal to Hispanics to hold onto power beyond the next few years. Latinos in Texas generally vote Democratic by a 2-to-1 margin, which won't be helped by a redistricting fight seen as a battle to maintain white control.

"It is obviously a high-risk strategy in a state that is increasingly Hispanic," said Michael Li, a Dallas-based election law lawyer who runs the blog "Texas Redistricting." Li is not involved in the redistricting fight.

SUPER TUESDAY NOT SUPER FOR ROMNEY

The redistricting mess has already affected the 2012 presidential race, notably the hopes of Mitt Romney, who may have done well in the Texas primary if it had taken place on Super Tuesday - March 6 - as originally scheduled.

Texas would have been the biggest prize up for grabs on Super Tuesday, when 10 other states held primaries and caucuses.

Romney, with far more money and a bigger campaign organization than rivals Rick Santorum and Newt Gingrich, was best placed to compete in so many states at once. Texas alone has 20 media markets, meaning statewide advertising can cost millions.

Winning or putting in a good showing in Texas would have boosted Romney. The state's 155 delegates, awarded proportionally, are a huge chunk of the 1,144 needed to become the nominee.

A strong performance on Super Tuesday also would have given Romney a badly needed breakthrough in the heart of southern Republican conservatism, weakening Santorum and perhaps cutting short what has become a protracted nomination fight.

Instead, Romney has been a weak front-runner and Santorum, a former Pennsylvania senator best known for strong religious conservatism, has been winning over the party's right wing.

"It (a March 6 Texas primary) would have changed a lot of things. It would have changed the entire complexion of Super Tuesday," said Matt Mackowiak, an Austin-based Republican strategist, especially with Santorum and Gingrich both vying for the support of the most conservative Texans.

"I suspect if the field was split and if Santorum and Gingrich hadn't had $5 million or $3 million to spend, then Romney probably would have won Texas on March 6," he said.

With Texas now one of the last states to vote, the nominee could be chosen by May 29. Even if it isn't, Santorum is now considered more likely to take Texas, thanks to improving fund-raising and his solidified position as the conservative alternative to Romney.

"Romney starts with a significant disadvantage in terms of public opinion," said Jim Henson, director of the Texas Politics Project at the University of Texas at Austin, although he added that Romney's big campaign war chest means that he could spend heavily in Texas to target clusters of mainstream conservatives in major media markets.

A Wilson Perkins Allen Opinion Research poll last week showed Santorum eight percentage points ahead of Romney among likely Republican primary voters in Texas. Santorum was at 35 percent to 27 percent for Romney.

Gingrich was at 20 percent and Ron Paul, a Texas congressman lagging in most polls, was at 8 percent.

The redistricting mess is affecting races down the ticket as well, with many voters not sure where they are registered and many candidates unsure of where they should run or raise money while the court fight has continued.

"I can look around the state and see the confusion in the eyes of the average voter," said Chris Elam, communications director for the state Republican party. Some 100 Republicans alone have applied to run for the 36 House seats, he said.

The interim map is expected to stand, but there is a chance it could be changed again by the Washington court.

The May 29 date is after schools close for the summer, leading to worries that turnout will be low, which often leads to unpredictable results.

The race to replace retiring Republican Senator Kay Bailey Hutchison has been most affected by the upheaval. Lieutenant Governor David Dewhurst has been favored to replace Hutchison, because of his statewide name recognition and fundraising prowess.

But the long delay has given opponents, especially Tea Party favorite Ted Cruz, time to raise money and their profiles. Former Dallas Mayor Tom Leppert and Craig James, a one-time television sports analyst, are also in the race.

If no one wins a majority on May 29, state law mandates a runoff vote on July 31, the heart of the hot Texas summer when an even smaller turnout would be expected.

(Editing by Alistair Bell and Cynthia Osterman)

Source: http://news.yahoo.com/redistricting-wrangle-hits-romney-texas-republicans-052541860.html

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Wednesday, March 21, 2012

Local Small Business SEO | Web Design Raleigh NC, SEO Raleigh ...

Better Image offers Search Engine Optimization specifically designed for local small businesses. Our affordable and local SEO services will help a small business have better placement in search engine results and increased revenue generated from the web.

There are hundreds of businesses competing for a particular service in Raleigh-Durham area yet only 10 of them are on the first page of Google Search results. The rest of them fail at generating more business, which is the main purpose of a small business website.

When most clients are ready for a redesign or just SEO services they usually want to jump directly into one or many of these traffic generating initiatives because they think that focusing on increasing traffic will help their business problem.

Instead, one should also take in consideration if the website is ready to receive the additional traffic and convert the visitors into high quality leads and customers.

As often happens, those who don?t truly understand SEO and Internet marketing and what it takes to create a successful online presence, are more interested in a quick fix than they are in making sure that things are done efficiently. In fact, most small business websites fail to bring more visitors because the owner or the person in charge of company?s Internet presence, approached this entire process in a completely wrong way. Hiring a SEO company out of the area, is the biggest mistake a local small business can make.

Efficient SEO involves knowledgeable research and strategy into the client?s local presence, needs, industry, competition, business model, keywords and target audience. Where do you rank now, and what keywords is that for? There is no magic number or time frame. Efficient SEO takes time and work. Efficient SEO also continues to require work after you?re number one. We can help you build your list of keywords and teach you how to be on the first page of Google search engine results.

Source: http://www.betterimage.org/local-small-business-seo

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Monday, March 19, 2012

g star shorts Automotive Mobile Audio Video Article Category ...

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Sunday, March 18, 2012

Motivation, the heart of self improvement | standout tall and be counted

?Have your heart in your life?s work, and be stout-hearted. Do something, act always, and do it now. Don?t be afraid. Many a man has been defeated by his doubts?lack of confidence. Take your risks ?you cannot eliminate them, you cannot escape them. You can diminish them by dominating them?. ~ Batten?s Wedge

This article is an excerpt from the book ?believe it and you will achieve it?. ?I hope you find it helpful like me.

Pain may sometimes be the reason why people change. Getting flunked grades make us realize that we need to study. Debts remind us of our inability to look for a source of income. Being humiliated gives us the ?push? to speak up and fight for ourselves to save our face from the next embarrassments. It may be a bitter experience, a friend?s tragic story, a great movie, or an inspiring book that will help us get up and get just the right amount of motivation we need in order to improve ourselves.

With the countless negativities the world brings about, how do we keep motivated? Try on the tips I prepared from A to Z?

A ? Achieve your dreams. Avoid negative people, things and places. Eleanor Roosevelt once said, ?the future belongs to those who believe in the beauty of their dreams.?

B ? Believe in yourself, and in what you can do.

C ? Consider things on every angle and aspect. Motivation comes from determination. To be able to understand life, you should feel the sun from both sides.

D ? Don?t give up and don?t give in. Thomas Edison failed once, twice, more than thrice before he came up with his invention and perfected the incandescent light bulb. Make motivation as your steering wheel.

E ? Enjoy. Work as if you don?t need money. Dance as if nobody?s watching. Love as if you never cried. Learn as if you?ll live forever. Motivation takes place when people are happy.

F ? Family and Friends ? are life?s greatest ?F? treasures. Don?t loose sight of them.

G ? Give more than what is enough. Where does motivation and self improvement take place at work? At home? At school? When you exert extra effort in doing things.

H ? Hang on to your dreams. They may dangle in there for a moment, but these little stars will be your driving force.

I ? Ignore those who try to destroy you. Don?t let other people to get the best of you. Stay out of toxic people ? the kind of friends who hates to hear about your success.

J ? Just be yourself. The key to success is to be yourself. And the key to failure is to try to please everyone.

K ? keep trying no matter how hard life may seem. When a person is motivated, eventually he sees a harsh life finally clearing out, paving the way to self improvement.

L ? Learn to love yourself. Now isn?t that easy?

M ? Make things happen. Motivation is when your dreams are put into work clothes.

N ? Never lie, cheat or steal. Always play a fair game.

O ? Open your eyes. People should learn the horse attitude and horse sense. They see things in 2 ways ? how they want things to be, and how they should be.

P ? Practice makes perfect. Practice is about motivation. It lets us learn repertoire and ways on how can we recover from our mistakes.

Q ? Quitters never win. And winners never quit. So, choose your fate ? are you going to be a quitter? Or a winner?

R ? Ready yourself. Motivation is also about preparation. We must hear the little voice within us telling us to get started before others will get on their feet and try to push us around. Remember, it wasn?t raining when Noah build the ark.

S ? Stop procrastinating.

T ? Take control of your life. Discipline or self control jives synonymously with motivation. Both are key factors in self improvement.

U ? Understand others. If you know very well how to talk, you should also learn how to listen. Yearn to understand first, and to be understood the second.

V ? Visualize it. Motivation without vision is like a boat on a dry land.

W ? Want it more than anything. Dreaming means believing. And to believe is something that is rooted out from the roots of motivation and self improvement.

X ? X Factor is what will make you different from the others. When you are motivated, you tend to put on ?extras? on your life like extra time for family, extra help at work, extra care for friends, and so on.

Y ? You are unique. No one in this world looks, acts, or talks like you. Value your life and existence, because you?re just going to spend it once.

Z ? Zero in on your dreams and go for it!!!

Conclusion

?Nobody has ever measured, not even poets, how much the heart can hold?. ~?Zelda Fitzgerald That is why when you put your heart to something it stands out. ?I have been practicing the above alphabet and it seems to have started working for me. Give it a try. bye for now and remember to always stand out tall and be counted.

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Source: http://insakanet.com/motivation-the-heart-of-self-improvement.html

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